Renal Function
Cockcraft-Gault Formula
The assessment tools contained in this Application ("Assessment Tools") are intended only to be an informational tool for clinicians who have been allowed access to the Application by Bl. The Assessment Tools are not intended to provide general or specific medical advice. The Assessment Tools do not take into account other considerations including, but not limited to, drug interactions, contraindications and patient history, and other risk factors. Therefore, the Application and Assessment Tools should be used as a general guide only and any specific advice provided by clinicians should be based on a professional review and consideration of each patient.
Renal function should be assessed by calculating the creatinine clearance (CrCL) prior to initiation of treatment with Pradaxa. Estimation of renal function using the Cockcroft-Gault formula is recommended, rather than eGFR.1
Treatment with Pradaxa in patients with severe renal impairment (CrCL < 30 ml/min) is contraindicated.1
While on treatment renal function should be assessed in certain clinical situations when it is suspected that the renal function could decline or deteriorate (such as hypovolaemia, dehydration, and with certain co-medications).1
Renal function should be assessed at least once a year in patients aged>75 years and in any patients with moderate renal impairment.1
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Renal Function

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